Growth Molecules · B
Nootkatone
A dry, bitter, almost metallic grapefruit character that no other material replicates. It adds lift and a modern edge to citrus blends, and it is the reference material for grapefruit in premium fragrance.
CAS number
4674-50-4
Olfactory family
Grapefruit
Minimum order
5 kg
Lead time
21-30 days
Short answer
Nootkatone (CAS 4674-50-4) is a biosynthetic aroma molecule in the Grapefruit family, produced by biological synthesis rather than extracted from a botanical. The signature grapefruit note, historically locked to grapefruit peel extraction. Industrial yeast fermentation in China has unlocked the market, and demand has been growing at more than 20%. Minimum order 5 kg, lead time 21-30 days. Every batch ships with a certificate of analysis, a safety data sheet and an IFRA conformity statement.
About Nootkatone
A dry, bitter, almost metallic grapefruit character that no other material replicates. It adds lift and a modern edge to citrus blends, and it is the reference material for grapefruit in premium fragrance.
Why it is on our list. The signature grapefruit note, historically locked to grapefruit peel extraction. Industrial yeast fermentation in China has unlocked the market, and demand has been growing at more than 20%.
Specification
| Specification | Value |
|---|---|
| CAS number | 4674-50-4 |
| Chinese name | 诺卡酮 |
| Material type | Biosynthetic aroma molecule (fermentation / biocatalysis) |
| Production route | Biological synthesis - not extracted from a botanical |
| Olfactory family | Grapefruit |
| Chinese olfactory family | 西柚/葡萄柚 |
| Perfume note position | Top-middle note |
| Purity | >= 90.0% |
| Physical form | Pale yellow to amber liquid or crystalline solid |
| Solubility | Soluble in alcohol and oils; insoluble in water |
| Applications | Home fragrance, Repellent & body care, Food & beverage |
| IFRA status | No category restriction |
| EU 1223/2009 allergen status | Not an Annex III named allergen |
| REACH | Registration dossier available on request |
| Food application | Approved food flavouring substance and a natural reference for grapefruit systems. |
| Shelf life | 24-36 months unopened, 12 months after opening |
| Storage | Store upright in the original sealed container, away from light, heat and air. Recommended 15-25 C. |
| Minimum order quantity | 5 kg |
| Lead time | 21-30 days |
Typical applications
- ✓Home fragrance
- ✓Repellent & body care
- ✓Food & beverage
Regulatory & compliance
IFRA
No category restriction under the IFRA standard in force at the date of purchase. The lot-specific conformity statement is supplied with every order.
EU 1223/2009 Annex III
Not a named Annex III fragrance allergen in its own right. Any allergen declaration for your finished product still has to account for every material you use, including the natural constituents of any botanical extracts in the blend.
REACH and export documents
REACH registration dossier available on request for EU shipments, together with the safety data sheet and the batch certificate of analysis.
Food application
Approved food flavouring substance and a natural reference for grapefruit systems.
Batch-specific values such as assay, density, refractive index, optical rotation and the full GC/MS chromatogram are issued with the certificate of analysis for the lot you receive. The values on this page are the standard profile for this material. The CAS number shown is the common main-component CAS; commercial material can be an isomer mixture, so the supplier COA is the reference.
Pricing
On request
Minimum order 5 kg · lead time 21-30 days · quote in 3-5 business days
Questions about this material
What is the minimum order quantity for Nootkatone?
+
5 kg. Smaller volumes are available as samples, typically 5-10 ml, so you can evaluate the material in your own formula before ordering a full drum.
Is Nootkatone an essential oil?
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No. Nootkatone is a biosynthetic aroma molecule produced by biological synthesis, and we describe it as a biosynthetic aroma raw material rather than a natural essential oil. The distinction matters for your labelling and for your customers: natural and biosynthetic materials are not interchangeable claims, even when the odour profile is.
What documentation comes with the order?
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The batch certificate of analysis, the safety data sheet, the IFRA conformity statement naming the standard and category that applies to your product, the REACH dossier where relevant, and lot traceability back to the production batch.
How long does it take to deliver?
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Lead time is currently 21-30 days for standard orders. We confirm the delivery date in the quotation, and we flag any capacity constraint before you place the order rather than after.
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